Tuesday, December 24, 2019

Comparison Between Pale Horse, Pale Rider By Katherine Ann...

Comparison Between Pale Horse, Pale Rider By Katherine Ann Porter And The Snows of Kilimanjaro By Ernest Hemingway This paper is going to discuss and analyze fully two short American fiction stories which are Pale horse, Pale Rider by Katherine Ann Porter and The Snows of Kilimanjaro by Ernest Hemingway. By reading the bibliographies of both these authors, one finds that Porter and Hemingway have met in a certain period of their life, where they could have shared lots of ideas and agreed on lots of different issues. By the end of reading both stories, one notices that there are lots of similarities found in both stories. One of the obviously noticed similarity is the autobiographical elements†¦show more content†¦The author effectively uses the dream to foreshadow the evil and tragedy that will affect Miranda from the world she lives in. after the dream the author moves the reader from the world of Mirandas imagination to the real world by stating an indirect everyday thought But let me get a fine yawn first. The dream world represents the real world. On the other hand, in The Snows of Kilimanjaro the fantasy world and memories of Harrys past are shown by an italic style of typed text, which can be easily determined. Most of Harrys (the protagonist) memories are of his past as a writer and his love affairs. Harry lives his life through his past, he regrets everything he done, hes mentally and physically ill. Harry is very bitter towards the woman, his companion on the wild African safari, his remarks were very cruel and harsh, for example you bitch, you rich bitch. Perhaps the inspiration of Harrys character came from Hemingway who was misogynist himself. Harry blames his failure on everyone but he havent got the cpurage to face reality and blame himself, she shot very well this good, this rich bitch, this kindly

Monday, December 16, 2019

Debut Albums and Champion Free Essays

That’s right, and you need to remember that all through this game I will conquer what has not been conquered Defeat will not be in my creed I will believe what others have doubted I will always endeavor to pull esteem, honor, and respect out of my team I have rained my mind and my body will follow I will acknowledge the fact that my opponent does not expect me to win But I will never surrender Weakness will not be in my heart I will look to my comrades and to those who are a part of me in this world and those who have trained me And I will draw strength from them I will gladly go out into the field of battle And I will move in everything I can do And I will reach my field of battle by any means at my disposal And when I get there, I will arrive violently I will rip the heart from my enemy, and leave it bleeding on the ground Because he annot stop me To my side I have comrades, comrades that have been with me through thick and thin Who have sacrificed their blood, sweat and tears Never will I let them fall, never will I let them down, and I will never leave an enemy behind Because our opponent does not know my heart No one will deny me, no one will define me And no one will tell me who and what I am and can be Belief will change my world It has moved continents, it has moved countries, it has put men on the moon And it will carry me through this battle I don’t understand those definitions I don’t understand when things go wrong I don’t understand mistakes But I do understand this: I understand victory, And I understand never surrendering No matter how bad things go my heart and my mind will carry my body through limits and weakness Who am l? I Today will be that day Not tomorrow, not next week, but right now, right here In your house and in your homes History will remember me I will not let worrying affect my cause I will define myself I will write my own pages And no one will tell me what I cannot be I will never give up Not until IVe given everything I got Because who am l? I AM A CHAMPION! The speech â€Å"I Am a Champion† by coach Flowers is an example of a strong voice. When he is attempting to pump up his players, his voice is extremely firm. He uses good diction like the word â€Å"bestowed† because he wants to be clear to his players so they know what his point is and what he is trying to portray. We will write a custom essay sample on Debut Albums and Champion or any similar topic only for you Order Now Also, he doesn’t stutter or use the word â€Å"like† at all during his speech. He wouldn’t use this voice to his elders or co-workers because they would think he is yelling at them or being rude. He only uses this to his players because he is encouraging them to play their hardest and go out there and win the championship. He also knows that they will listen to him because he is the one that taught them everything and he determines how good they will play. Coach Flowers also does not stutter or use â€Å"like† one time in his speech. This shows that he is prepared and he knows what he is talking about. A Strong voice is determined by all of those factors that I described and I believe that coach Flowers does have a strong voice. How to cite Debut Albums and Champion, Papers

Saturday, December 7, 2019

Clinical Research Investigator

Question: Describe about the major responsibilities of a clinical research investigator? Answer: Introduction: Clinical research is a research which requires group of people to examine the safety, tolerance, dose and action of a drug. Clinical research obeys a pre- planned protocol. Clinical trial is also known as clinical research. A clinical investigator regulates the full method of clinical research. And the clinical investigator is responsible for all the process. Clinical investigators have so many responsibilities. And the investigator should follow them to get a perfect and appropriate result of the clinical research. It is mandatory to check and follow the plan of clinical research because a fail of clinical research means wastage of huge money. So all the member who are associated to clinical research should have enough knowledge to achieve the goal. Body: The clinical investigators regulate good clinical practice. The clinical investigators prepare a design of the clinical research and also maintain the quality of the clinical research. A good clinical practice is delivered by International Conference of Harmonization Guidelines (investigator responsibilities - regulation and clinical trials, 2015). Good Clinical Practice is a standard for conduct, monitoring, design, performance, reporting, auditing of clinical trials that produces guarantee that the reported results and data are believable and precise. The design of clinical trial certifies the integrity and quality of data which are assembled in clinical trial and also secures the safety, rights and welfare of participants of research. The whole clinical research is performed in the supervision of the clinical investigator. The clinical research investigator is an independent person who actually organizes a clinical research. By the instant direction the new drug is distribut ed to a subject (Guidance for Industry Investigator Responsibilities Protecting the Rights, Safety, and Welfare of Study Subjects, 2015). The investigation is regulated by a team of persons and the head is the clinical research investigator in the whole team. The investigator is also responsible for each of the opinion of the whole team. The investigator conducts and begins the investigations. The clinical research investigator has the power to control and stop the research immediately. The clinical research investigator should have appropriate knowledge to perform, conduct, design, monitoring the whole research. It is the responsibility of the clinical research investigator to supervise and conduct the research process. The investigator should inform the subject initially that it is the investigational process of new drug development. The clinical research investigator has some general responsibilities, and also they control the drug which is used for the research (Ccr.med.keio.ac .jp, 2015). It is the responsibility of the clinical research investigator to keep the record and hold the record for further investigation. The clinical research investigator should maintain the sufficient record of the character of the drug. It is the responsibility of clinical research investigator to keep all clinical data and also precise case history. The investigator should maintain the data appropriate to the investigation on each person administered and also investigational drug which is used as control (Baer et al., 2011). An investigator is needed to preserve all the clinical record data. The clinical trial data are preserved for two years because two years are required for the approval of the marketing application for the investigational drugs. The drug is investigated for the approval of marketing application. After two years the investigation is terminated if the marketing application is not approved. There are four investigator reports. And the reports are safety repo rts, progress report, final report and financial disclosure. It is the responsibility of the investigator to cover any adverse effects that is shocking or life threatening or serious or surprising. The clinical research investigator punctually covers any adverse event which is caused by the drug (roles and responsibilities in clinical trial, 2015). The clinical research investigator responsibilities are control of investigational drug, record holding and keeping and report forming. The clinical research investigator is disqualificated if the frequently intentional failure is observed. So the responsibility of the investigator is very important. Food and Drug Administration delivers a notice to the clinical research investigator and gives a chance to explain. Conclusion: The responsibility of the clinical research investigator is very crucial. And the clinical research investigator is responsible for the whole process (Nichd.nih.gov, 2015). A set of people or a specific person in required in clinical research. Their actions or tissues are needed for the study of clinical research. So the full method is very critical to handle. And the responsibility of a investigator is very important because the whole method of clinical research depends on the clinical research investigator. A predefined procedure or a master plan is needed for developing a clinical research. And this predefined procedure or master plan is created by the clinical research investigator. So the responsibility of the clinical research investigator is very important and significant. References: Baer, A., Devine, S., Beardmore, C. and Catalano, R. (2011). Clinical Investigator Responsibilities.Journal of Oncology Practice, 7(2), pp.124-128. Ccr.med.keio.ac.jp, (2015).Module 3: Investigator Role Responsibilities. [online] Available at: https://www.ccr.med.keio.ac.jp/e_learning/UM_E-Learning_US/mod03/index.html [Accessed 10 Mar. 2015]. Guidance for Industry Investigator Responsibilities Protecting the Rights, Safety, and Welfare of Study Subjects. (2015). [online] Available at: https://www.fda.gov/downloads/Drugs/.../Guidances/UCM187772.pdf [Accessed 10 Mar. 2015]. investigator responsibilities - regulation and clinical trials. (2015). [online] Available at: https://www.fda.gov/downloads/Training/ClinicalInvestigatorTrainingCourse/UCM283301.pdf [Accessed 10 Mar. 2015]. Nichd.nih.gov, (2015).Clinical Trials Clinical Research. [online] Available at: https://www.nichd.nih.gov/health/clinicalresearch/Pages/index.aspx [Accessed 10 Mar. 2015]. roles and responsibilities in clinical trial. (2015). [online] Available at: https://www.centerwatch.com/pdfs/s11604_ch4.pdf [Accessed 10 Mar. 2015].